The global epidemic of obesity is taking over many parts of the world and represents a major public health challenge. The prognosis for North Americans is poor and unfortunately, it’s getting worse for children, adolescents, and adults alike; not only are we seeing climbing body weights but we are also seeing more and more bulging waistlines, which is indicative of the dangerous belly fat that surrounds our organs [1-4]. Supplementing with omega-3 fish oil seems to be a safe, inexpensive, and effective option that can help us prevent and treat this serious health concern.
Omega-3 fatty acids are low in overweight/obese subjects
Body mass index (BMI) is a number that is calculated from a person’s weight and height. It is used as a screening tool to identify possible weight problems. Research reveals that lower body levels of omega-3 fatty acids are associated with higher BMI results, meaning that improving your omega-3 levels may reduce the risk of having a weight problem [5-7]. Although BMI is a popular screening tool, it has major limitations because it isn’t able to discriminate between fat and lean (muscle) mass; it has been suggested that body fat percentage plays a more important role in distinguishing between healthy and unhealthy individuals [8, 9].
Belly fat in particular is especially dangerous and is considered to be more predictive of poor health than BMI [10, 11]. Low omega-3 fatty acids also seem to play a role in the accumulation of belly fat[5, 12]. In fact, higher omega-3 fatty acid levels may reduce belly fat by decreasing fat cell size . These results suggest that dietary management with omega-3 fatty acids may represent an important way to better manage BMI and belly fat.
Supplementing with omega-3 fish oil results in weight loss
Omega-3 fish oil supplementation has been shown to be effective for promoting not only weight loss but also fat loss and belly fat loss in various trials; dosages have ranged from 300 mg to 1.8 grams daily of EPA+DHA [14-18]. The addition of omega-3 fatty acids to an exercise program also seems to boost fat loss potential[19, 20]. Likewise, the addition of seafood or fish oil to a nutritionally balanced calorie-restricted diet seems to boost weight loss potential [21, 22]. This begs the question: does combining omega-3 fatty acid supplementation with both diet and exercise provide even more significant results? The answer is yes!
In a short 3-week clinical trial, people who combined 2.8 grams daily of omega-3 fatty acid supplementation (2:1 ratio of EPA to DHA) with both calorie restriction and regular exercise experienced a 1.5 kg (3.3 lb) greater weight loss compared to those consuming a placebo, following a calorie-restricted diet, and exercising . Therefore, supplementing with omega-3 fatty acids can improve body composition but combining supplementation with calorie restriction and/or exercise further accelerates the weight/fat loss process.
How does it work?
Omega-3 fatty acids may contribute to improved body composition by increasing metabolism and fat burning potential [23-27]. They also seem to suppress appetite, which leads to the consumption of fewer calories [28, 29].
Omega-3 improves the metabolic consequences of obesity
For many years, excess body fat was thought to be simply a storage space for extra calories. However, overwhelming evidence in recent years has revealed that excess body fat has severe consequences within the body, such as inflammation, insulin resistance, high triglycerides, and many others [30-34]. An increased omega-3 fatty acid intake has been shown to attenuate many of these consequences [14, 15, 17, 21, 25, 35-46]. Therefore, omega-3 fatty acid supplementation may not only improve weight/fat loss but it may also offer additional benefits in managing the serious consequences of obesity.
Omega-3 fatty acids found in fish oil supplements seem to offer a breadth of health benefits in regards to obesity and cannot be ignored. Therefore, adding fish oil to your daily regime might be worth considering!
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1. Flegal, K.M., et al., Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA, 2012. 307(5): p. 491-7.
2. Katzmarzyk, P.T. and C. Mason, Prevalence of class I, II and III obesity in Canada. CMAJ, 2006. 174(2): p. 156-7.
3. Gotay, C.C., et al., Updating the canadian obesity maps: An epidemic in progress. Can J Public Health, 2013. 104(1).
4. Ford, E.S., et al., Trends in obesity and abdominal obesity among adults in the United States from 1999-2008. Int J Obes (Lond), 2011. 35(5): p. 736-43.
5. Micallef, M., et al., Plasma n-3 Polyunsaturated Fatty Acids are negatively associated with obesity. Br J Nutr, 2009. 102(9): p. 1370-4.
6. Saito, E., et al., Docosahexaenoic acid content in plasma phospholipids and desaturase indices in obese children. J Atheroscler Thromb, 2011. 18(4): p. 345-50.
7. Burrows, T., C.E. Collins, and M.L. Garg, Omega-3 index, obesity and insulin resistance in children. Int J Pediatr Obes, 2011. 6(2-2): p. e532-9.
8. Goonasegaran, A.R., F.N. Nabila, and N.S. Shuhada, Comparison of the effectiveness of body mass index and body fat percentage in defining body composition. Singapore Med J, 2012. 53(6): p. 403-8.
9. Chang, S.H., et al., A systematic review of body fat distribution and mortality in older people. Maturitas, 2012. 72(3): p. 175-91.
10. Lee, C.M., et al., Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis. J Clin Epidemiol, 2008. 61(7): p. 646-53.
11. Coutinho, T., et al., Central obesity and survival in subjects with coronary artery disease: a systematic review of the literature and collaborative analysis with individual subject data. J Am Coll Cardiol, 2011. 57(19): p. 1877-86.
12. Garaulet, M., et al., Site-specific differences in the fatty acid composition of abdominal adipose tissue in an obese population from a Mediterranean area: relation with dietary fatty acids, plasma lipid profile, serum insulin, and central obesity. Am J Clin Nutr, 2001. 74(5): p. 585-91.
13. Garaulet, M., et al., Relationship between fat cell size and number and fatty acid composition in adipose tissue from different fat depots in overweight/obese humans. Int J Obes (Lond), 2006. 30(6): p. 899-905.
14. Ebrahimi, M., et al., Omega-3 fatty acid supplements improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity. Acta Cardiol, 2009. 64(3): p. 321-7.
15. Crochemore, I.C., et al., omega-3 polyunsaturated fatty acid supplementation does not influence body composition, insulin resistance, and lipemia in women with type 2 diabetes and obesity. Nutr Clin Pract, 2012. 27(4): p. 553-60.
16. Kabir, M., et al., Treatment for 2 mo with n 3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study. Am J Clin Nutr, 2007. 86(6): p. 1670-9.
17. Lopez-Alarcon, M., et al., Supplementation of n3 long-chain polyunsaturated fatty acid synergistically decreases insulin resistance with weight loss of obese prepubertal and pubertal children. Arch Med Res, 2011. 42(6): p. 502-8.
18. Vasickova, L., P. Stavek, and P. Suchanek, Possible effect of DHA intake on body weight reduction and lipid metabolism in obese children. Neuro Endocrinol Lett, 2011. 32 Suppl 2: p. 64-7.
19. Warner, J.G., Jr., et al., Combined effects of aerobic exercise and omega-3 fatty acids in hyperlipidemic persons. Med Sci Sports Exerc, 1989. 21(5): p. 498-505.
20. Hill, A.M., et al., Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors. Am J Clin Nutr, 2007. 85(5): p. 1267-74.
21. Mori, T.A., et al., Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects. Am J Clin Nutr, 1999. 70(5): p. 817-25.
22. Thorsdottir, I., et al., Randomized trial of weight-loss-diets for young adults varying in fish and fish oil content. Int J Obes (Lond), 2007. 31(10): p. 1560-6.
23. Kunesova, M., et al., The influence of n-3 polyunsaturated fatty acids and very low calorie diet during a short-term weight reducing regimen on weight loss and serum fatty acid composition in severely obese women. Physiol Res, 2006. 55(1): p. 63-72.
24. Couet, C., et al., Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults. Int J Obes Relat Metab Disord, 1997. 21(8): p. 637-43.
25. Guebre-Egziabher, F., et al., Nutritional intervention to reduce the n-6/n-3 fatty acid ratio increases adiponectin concentration and fatty acid oxidation in healthy subjects. Eur J Clin Nutr, 2008. 62(11): p. 1287-93.
26. Matheson, K.M., et al., n-3 polyunsaturated fatty acids increase thermic effect of food in men with metabolic syndrome. Can J Diet Pract Res, 2011. 72(4): p. 201-4.
27. Vaughan, R.A., et al., Conjugated linoleic acid or omega 3 fatty acids increase mitochondrial biosynthesis and metabolism in skeletal muscle cells. Lipids Health Dis, 2012. 11: p. 142.
28. Parra, D., et al., A diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight loss. Appetite, 2008. 51(3): p. 676-80.
29. Harden, C.J., et al., Effect of different long-chain fatty acids on cholecystokinin release in vitro and energy intake in free-living healthy males. Br J Nutr, 2012. 108(4): p. 755-8.
30. Tack, C.J., et al., Inflammation links excess fat to insulin resistance: the role of the interleukin-1 family. Immunol Rev, 2012. 249(1): p. 239-52.
31. Monteiro, R. and I. Azevedo, Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm, 2010. 2010.
32. Ikeoka, D., J.K. Mader, and T.R. Pieber, Adipose tissue, inflammation and cardiovascular disease. Rev Assoc Med Bras, 2010. 56(1): p. 116-21.
33. Suliga, E., Visceral adipose tissue in children and adolescents: a review. Nutr Res Rev, 2009. 22(2): p. 137-47.
34. Rabe, K., et al., Adipokines and insulin resistance. Mol Med, 2008. 14(11-12): p. 741-51.
35. Mohammadi, E., et al., Effects of omega-3 fatty acids supplementation on serum adiponectin levels and some metabolic risk factors in women with polycystic ovary syndrome. Asia Pac J Clin Nutr, 2012. 21(4): p. 511-8.
36. Moreno-Aliaga, M.J., S. Lorente-Cebrian, and J.A. Martinez, Regulation of adipokine secretion by n-3 fatty acids. Proc Nutr Soc, 2010. 69(3): p. 324-32.
37. Itoh, M., et al., Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler Thromb Vasc Biol, 2007. 27(9): p. 1918-25.
38. Simao, A.N., et al., Blood pressure decrease with ingestion of a soya product (kinako) or fish oil in women with the metabolic syndrome: role of adiponectin and nitric oxide. Br J Nutr, 2012. 108(8): p. 1435-42.
39. Neff, L.M., et al., Algal docosahexaenoic acid affects plasma lipoprotein particle size distribution in overweight and obese adults. J Nutr, 2011. 141(2): p. 207-13.
40. Kiecolt-Glaser, J.K., et al., Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial. Brain Behav Immun, 2012. 26(6): p. 988-95.
41. Kalupahana, N.S., K.J. Claycombe, and N. Moustaid-Moussa, (n-3) Fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights. Adv Nutr, 2011. 2(4): p. 304-16.
42. Itariu, B.K., et al., Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: a randomized controlled trial. Am J Clin Nutr, 2012. 96(5): p. 1137-49.
43. Dangardt, F., et al., Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents. Atherosclerosis, 2010. 212(2): p. 580-5.
44. Rudkowska, I., et al., Effects of a supplementation of n-3 polyunsaturated fatty acids with or without fish gelatin on gene expression in peripheral blood mononuclear cells in obese, insulin-resistant subjects. J Nutrigenet Nutrigenomics, 2011. 4(4): p. 192-202.
45. Ramel, A., et al., Beneficial effects of long-chain n-3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adults. Diabetologia, 2008. 51(7): p. 1261-8.
46. Ramel, A., et al., Effects of seafood consumption and weight loss on fasting leptin and ghrelin concentrations in overweight and obese European young adults. Eur J Nutr, 2009. 48(2): p. 107-14.